{"id":15310,"date":"2025-05-28T22:50:49","date_gmt":"2025-05-28T22:50:49","guid":{"rendered":"https:\/\/topat10.com\/?p=15310"},"modified":"2025-05-28T22:50:49","modified_gmt":"2025-05-28T22:50:49","slug":"mushroom-supplements-are-the-biohackers-latest-fix-2025","status":"publish","type":"post","link":"https:\/\/topat10.com\/?p=15310","title":{"rendered":"Mushroom Supplements Are the Biohackers\u2019 Latest Fix (2025)"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div>\n<p><span class=\"lead-in-text-callout\">From ancient remedies<\/span> to your Amazon cart, mushroom supplements have traveled a circuitous road. They nourish the body, <a href=\"https:\/\/www.wired.com\/story\/breeding-stronger-magic-mushrooms\/\" target=\"_blank\">enhance the mind<\/a>, and occasionally poison the unlucky. Their biochemical adaptability has intrigued Eastern cultures for centuries. The West has been slow to embrace mushrooms until the 21st century, propelled in part by endorsements from celebrities like Gisele B\u00fcndchen and Gwen Stefani.<\/p>\n<p class=\"paywall\">Today, in a zeitgeist fixated on <a href=\"https:\/\/www.wired.com\/category\/gear\/products\/health-fitness\/\">biohacking and self-optimization<\/a>, mushrooms are now tools for functional wellness. Gone are the days of foraging and saut\u00e9ing. Instead, we embrace microdosing. We\u2019re enjoying lion\u2019s mane in our adaptogenic lattes and mixing cordyceps into our post-workout smoothies, aiming to enhance our brains and upgrade our immune systems. Researchers are also exploring their potential applications, ranging from <a href=\"https:\/\/www.cancer.gov\/about-cancer\/treatment\/cam\/patient\/mushrooms-pdq\" target=\"_blank\">cancer therapies<\/a> to supportive treatments for <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10532592\/\" target=\"_blank\">COVID-19<\/a>.<\/p>\n<div class=\"TableOfContentWrapper-jyvRts czfrZC table-of-content\">\n<div data=\"[object Object]\" class=\"AccordionWrapper-hIuJtK bCzlaC\">\n<div class=\"AccordionItemWrapper-eGPSID czXIDr\">\n<div class=\"AccordionContainer-fEnXXG iiuTyf\">\n<div data-testid=\"accordion-item-container\" class=\"AccordionItemContainer-jbkqX ckSoPI\">\n<p><strong>Table of Contents<\/strong><\/p>\n<p><button class=\"BaseButton-bLlsy ButtonWrapper-xCepQ fhIjxp fCyinQ button button--utility AccordionItemContainerButton-eCWroF cGXmWk\" data-event-click=\"{&quot;element&quot;:&quot;Button&quot;}\" data-testid=\"Button\" role=\"button\" type=\"button\"><span class=\"ButtonLabel-cjAuJN bBWXSg button__label\">AccordionItemContainerButton<\/span><\/button><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p class=\"paywall\"><strong><a href=\"https:\/\/www.wired.com\/v2\/offers\/wir_generic_ctrl?source=Site_0_HCL_WIR_EDIT_HARDCODED_0_COMMERCE_AFFILIATE_ZZ\"><em>Power up with unlimited access to<\/em> WIRED<\/a><em>.<\/em><\/strong> <em>Get best-in-class reporting that&#8217;s too important to ignore for just <del>$2.50<\/del> $1 per month for 1 year. Includes unlimited digital access and exclusive subscriber-only content. <a href=\"https:\/\/www.wired.com\/v2\/offers\/wir_generic_ctrl?source=Site_0_HCL_WIR_EDIT_HARDCODED_0_COMMERCE_AFFILIATE_ZZ\">Subscribe Today<\/a><\/em>.<\/p>\n<p><h2 class=\"paywall\">What Are Functional Mushrooms?<\/h2>\n<\/p>\n<p class=\"paywall\">Functional mushrooms, often referred to as medicinal or adaptogenic, offer more than just nutritional value. The excitement surrounding them isn\u2019t due to recent studies; their advantages <a href=\"https:\/\/www.wired.com\/story\/adaptogenic-drinks-the-race-to-make-your-coffee-do-more-and-more\/\" target=\"_blank\">have been recognized<\/a> for years. What has shifted is the way they are presented, allowing for simpler integration into contemporary lifestyles without the need for cooking. Brands like <a data-offer-url=\"https:\/\/www.amazon.com\/RYZE-Mushroom-Adaptogenic-Mushrooms-Digestion\/dp\/B0DJWV4BQ1\/ref=asc_df_B0DJWV4BQ1\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/cna.st\/affiliate-link\/FX1LF4r6izvTB7YiWdVoZ7S2QMwao23jxfFAdUSPtgqweFBaeVLB29NYLDpNVmEvqfLa5Sg5Q8eGkfiX8BJPta3doexP2m7YkQSov1VfCbQYm9jcDphSsDZzh2DFTeQiduNLMihrNPLQi5ggTq4iXu6GzmWAyJoxz6E49DGxuenYqwVzHj323cXQxUzHLV2asbi6RDbB8oNhXgPhzRWWS2J6NA1v8JbYKRPQ&quot;}\" href=\"https:\/\/cna.st\/affiliate-link\/FX1LF4r6izvTB7YiWdVoZ7S2QMwao23jxfFAdUSPtgqweFBaeVLB29NYLDpNVmEvqfLa5Sg5Q8eGkfiX8BJPta3doexP2m7YkQSov1VfCbQYm9jcDphSsDZzh2DFTeQiduNLMihrNPLQi5ggTq4iXu6GzmWAyJoxz6E49DGxuenYqwVzHj323cXQxUzHLV2asbi6RDbB8oNhXgPhzRWWS2J6NA1v8JbYKRPQ\" rel=\"sponsored\" target=\"_blank\">RYZE<\/a> and <a data-offer-url=\"https:\/\/plantfusion.com\/products\/mushroom-protein-powder\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/cna.st\/affiliate-link\/2YfVS2JkEsZbEYgcRCNmcRWRBiAEqzuSUiUxRAACBDLbmUA1sSAJafUjU6aV8sDTPBgwPUqcz9Bk9GyARVPxPhNzQDpiYcEotKTnxG5WFUr5tPeeW34D88cuYSc2jJ41EfKUh9LjTPNM8zm5bmnWHd7u3RKeNCREtNW&quot;}\" href=\"https:\/\/cna.st\/affiliate-link\/2YfVS2JkEsZbEYgcRCNmcRWRBiAEqzuSUiUxRAACBDLbmUA1sSAJafUjU6aV8sDTPBgwPUqcz9Bk9GyARVPxPhNzQDpiYcEotKTnxG5WFUr5tPeeW34D88cuYSc2jJ41EfKUh9LjTPNM8zm5bmnWHd7u3RKeNCREtNW\" rel=\"sponsored\" target=\"_blank\">PlantFusion<\/a> have played a significant role in transforming these fungi from traditional remedies to nootropic supplements.<\/p>\n<p class=\"paywall\">\u201cOne of the OG brands was <a data-offer-url=\"https:\/\/www.amazon.com\/Four-Sigmatic-Cordyceps-Mushroom-Elixir\/dp\/B00MMHVDXM\/ref=sr_1_1\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/cna.st\/affiliate-link\/731Y1jnnp3aqDjbWMHpb21W2THJEgzmMuyHUSu9LyEamb2ekg6g8Km9QSgfKLdbYfcmJdgjMWVdWfGJx7CeuN3pdvCsY5yHy587G8a2kKJovp9kbxqwEJPfsQHoRRFp2hXEd6LyMXkC2gZYSrTrpHpb9Je8oPqxTg6GeDsf6yyB77DAztc3jxnoMYWqjvVAPB26msT31dHjvA&quot;}\" href=\"https:\/\/cna.st\/affiliate-link\/731Y1jnnp3aqDjbWMHpb21W2THJEgzmMuyHUSu9LyEamb2ekg6g8Km9QSgfKLdbYfcmJdgjMWVdWfGJx7CeuN3pdvCsY5yHy587G8a2kKJovp9kbxqwEJPfsQHoRRFp2hXEd6LyMXkC2gZYSrTrpHpb9Je8oPqxTg6GeDsf6yyB77DAztc3jxnoMYWqjvVAPB26msT31dHjvA\" rel=\"sponsored\" target=\"_blank\">Four Sigmatic<\/a>,\u201d recalls Brigitte Zeitlin, a NYC-based nutritionist who has swapped caffeine for mushroom coffee and matcha tea. \u201cWhen they first hit shelves, people were like, \u2018Wait, we drink mushrooms now?\u2019.\u201d<\/p>\n<p class=\"paywall\">\u201cIf you don\u2019t like the taste or can\u2019t find quality mushrooms at your store, supplements are a great second option,\u201d she adds. \u201cSome people hate swallowing pills or are already taking too many, so <a href=\"https:\/\/www.wired.com\/gallery\/best-protein-powders\/\" target=\"_blank\">powders are a great alternative<\/a> because they&#8217;re already broken down.\u201d<\/p>\n<p><h2 class=\"paywall\">A <em>Very<\/em> Brief History<\/h2>\n<\/p>\n<p class=\"paywall\">For as long as humans have been getting sick, they have relied on fungi as a means of healing. Hippocrates is said to have used amadou, a spongy fungus, to reduce inflammation. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26854098\/\">\u00d6tzi the Iceman<\/a> had amadou in his supplies (probably for fire-starting), along with birch polypore, which was likely used to fight intestinal parasites. Native American cultures pressed puffball mushrooms onto wounds to halt bleeding and aid healing. Additionally, they used <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC8175741\/#:~:text=Tiger%20milk%20mushroom%20(TMM%3B%20Lignosus,different%20ailments%2C%20including%20respiratory%20disorders.\">tiger milk mushrooms<\/a> to treat asthma.<\/p>\n<p class=\"paywall\">East Asian traditions have long used Phellinus fungi to treat <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/abs\/pii\/S0308814622016934\" target=\"_blank\">digestive issues<\/a>. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK92757\/\" target=\"_blank\"><em>Ganoderma lucidum<\/em><\/a>\u2014commonly known as reishi or lingzhi\u2014was first recorded in the <a href=\"https:\/\/www.sciencedirect.com\/topics\/agricultural-and-biological-sciences\/shennong\" target=\"_blank\"><em>Shen Nong Ben Cao Jing<\/em><\/a>, the oldest Chinese pharmacopeia written over two millennia ago, where it was classified as a tonic for anti-aging and <a href=\"https:\/\/www.cancer.gov\/Common\/PopUps\/popDefinition.aspx?id=454782&amp;version=healthprofessional&amp;language=English&amp;dictionary=Cancer.gov\" target=\"_blank\">boosting qi<\/a>. In modern-day China, reishi is often recommended to support immune health in <a href=\"https:\/\/www.cancer.gov\/about-cancer\/treatment\/cam\/hp\/mushrooms-pdq#_128\" target=\"_blank\">patients undergoing chemotherapy<\/a> or radiation.<\/p>\n<p class=\"paywall\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38116085\/\" target=\"_blank\"><em>Inonotus obliquus<\/em><\/a>\u2014better known as chaga\u2014has been a staple in traditional medicine among Indigenous communities across the world. Notably, native Siberians would grind up chaga and add it to teas, soups, and stews, believing it to ward off degenerative diseases. It was also a remedy for ulcers, liver ailments, and tuberculosis. Russian First Nations used it to slow the growth of visible tumors. Today, hunters in rural Russia still consume chaga to boost endurance on long treks.<\/p>\n<p><h2 class=\"paywall\">Are Mushroom Supplements Good for You?<\/h2>\n<\/p>\n<figure class=\"AssetEmbedWrapper-eVDQiB byBkf asset-embed\">\n<div class=\"AssetEmbedAssetContainer-eJxoAx dBHGoQ asset-embed__asset-container\"><span class=\"SpanWrapper-umhxW lgCwTv responsive-asset AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset\"><picture class=\"ResponsiveImagePicture-cWuUZO dUOtEa AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset responsive-image\"><noscript><img decoding=\"async\" alt=\"Image may contain Fungus Ling Zhi Mushroom and Plant\" class=\"ResponsiveImageContainer-eybHBd fptoWY responsive-image__image lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_1600%2Cc_limit\/503078154\" data-sizes=\"auto\" data-srcset=\"https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_120,c_limit\/503078154 120w, https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_240,c_limit\/503078154 240w, https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_320,c_limit\/503078154 320w, https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_640,c_limit\/503078154 640w, https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_960,c_limit\/503078154 960w, https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_1280,c_limit\/503078154 1280w, https:\/\/media.wired.com\/photos\/682aa086c9c3210c69e5f9bd\/master\/w_1600,c_limit\/503078154 1600w\" sizes=\"100vw\"\/><\/noscript><\/picture><\/span><\/div>\n<p><span class=\"BaseWrap-sc-gjQpdd BaseText-ewhhUZ CaptionCredit-ejegDm iUEiRd isTgyB fNaHcW caption__credit\">Photograph: Getty Images<\/span><\/p>\n<\/figure>\n<p class=\"paywall\">Nutritionists agree: food first. Whole mushrooms like maitake, shiitake, and lion\u2019s mane offer fiber and nutrients you won\u2019t get from supplements. Toss them into stir-fries, omelets, or soups. While supplements don&#8217;t always deliver the same results, here are some of the health benefits seen with regular intake.<\/p>\n<p>It may decrease the chance of cancer.<\/p>\n<p class=\"paywall\">A <a href=\"https:\/\/academic.oup.com\/advances\/advance-article-abstract\/doi\/10.1093\/advances\/nmab015\/6174025\" target=\"_blank\">review<\/a> of 17 cancer studies shows that consuming about 1\/8 cup of mushrooms a day may lower your risk of cancer by as much as 45 percent. Fungi are packed with ergothioneine, an amino acid and antioxidant that slows cellular damage. Shiitake, oyster, maitake, and king oyster have some of the higher amounts of ergothioneine, but any variety of mushrooms is better than none.<\/p>\n<p>It can help protect brain health.<\/p>\n<p class=\"paywall\">In a <a data-offer-url=\"https:\/\/content.iospress.com\/articles\/journal-of-alzheimers-disease\/jad180959\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/content.iospress.com\/articles\/journal-of-alzheimers-disease\/jad180959&quot;}\" href=\"https:\/\/content.iospress.com\/articles\/journal-of-alzheimers-disease\/jad180959\" rel=\"nofollow noopener\" target=\"_blank\">study<\/a> in Singapore, participants who ate more than two cups of mushrooms (golden, oyster, shiitake, and white button) a week had a 50 percent lower risk of developing mild cognitive impairment.<\/p>\n<p>It encourages a healthy gut.<\/p>\n<p class=\"paywall\">Unlike many foods that are broken down by stomach acid, <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10358859\/\" target=\"_blank\">the polysaccharides in fungi<\/a> remain intact as they pass through the stomach. This allows them to reach the colon, where they can prompt the growth of healthy bacteria.<\/p>\n<p>It can contribute to a healthy immune system.<\/p>\n<p class=\"paywall\"><a data-offer-url=\"https:\/\/www.uclahealth.org\/news\/article\/7-health-benefits-of-mushrooms\" class=\"external-link\" data-event-click=\"{&quot;element&quot;:&quot;ExternalLink&quot;,&quot;outgoingURL&quot;:&quot;https:\/\/www.uclahealth.org\/news\/article\/7-health-benefits-of-mushrooms&quot;}\" href=\"https:\/\/www.uclahealth.org\/news\/article\/7-health-benefits-of-mushrooms\" rel=\"nofollow noopener\" target=\"_blank\">Certain shrooms also provide vital nutrients<\/a> that can support your overall well-being. Cremini and portobello are high in selenium, a mineral that produces antioxidant enzymes to prevent cell damage. Maitake mushrooms are a great source of vitamin D, and incorporate Shiitake into your diet for vitamin B6.<\/p>\n<p><h2 class=\"paywall\">The Top Functional Mushrooms, Explained<\/h2>\n<\/p>\n<figure class=\"AssetEmbedWrapper-eVDQiB byBkf asset-embed\">\n<div class=\"AssetEmbedAssetContainer-eJxoAx dBHGoQ asset-embed__asset-container\"><span class=\"SpanWrapper-umhxW lgCwTv responsive-asset AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset\"><picture class=\"ResponsiveImagePicture-cWuUZO dUOtEa AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset responsive-image\"><noscript><img decoding=\"async\" alt=\"Image may contain Chaga Mushroom Fungi Birch and Tree\" class=\"ResponsiveImageContainer-eybHBd fptoWY responsive-image__image lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_1600%2Cc_limit\/1355961025\" data-sizes=\"auto\" data-srcset=\"https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_120,c_limit\/1355961025 120w, https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_240,c_limit\/1355961025 240w, https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_320,c_limit\/1355961025 320w, https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_640,c_limit\/1355961025 640w, https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_960,c_limit\/1355961025 960w, https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_1280,c_limit\/1355961025 1280w, https:\/\/media.wired.com\/photos\/682a980af72e149bf0e79751\/master\/w_1600,c_limit\/1355961025 1600w\" data-sizes=\"100vw\"\/><\/noscript><\/picture><\/span><\/div>\n<p><span class=\"BaseWrap-sc-gjQpdd BaseText-ewhhUZ CaptionCredit-ejegDm iUEiRd isTgyB fNaHcW caption__credit\">Photograph: Ksenia Shestakova\/Getty Images<\/span><\/p>\n<\/figure>\n<p class=\"paywall\">From nootropic lattes to adaptogenic powders, certain species have become stars in the wellness space. Here&#8217;s what the research and experts have to say about the fungi dominating your feed.<\/p>\n<p class=\"paywall\">Chaga, a white-rot fungus that thrives on birch trees in northern climates, is recognized for its abundant antioxidants. \u201cIf you have autoimmune issues like Hashimoto\u2019s or psoriasis, Chaga mushrooms are awesome because they reduce inflammation,\u201d says Zeitlin. Though <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/39170453\/\" target=\"_blank\">much of the research<\/a> has been conducted in vitro or on animals, Chaga demonstrates promising antimicrobial, anti-diabetic, and anti-inflammatory effects.<\/p>\n<p class=\"paywall\">Cordyceps is a parasitic fungus that sprouts on larvae of insects. In wellness marketing, it&#8217;s the performance mushroom and a favorite among athletes. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC7717596\/\" target=\"_blank\">Research suggests<\/a> cordyceps may help improve stamina and post-workout recovery by boosting ATP production and oxygen efficiency in cells. But many of those claims are based on early-stage research and lab models.<\/p>\n<div class=\"GenericCalloutWrapper-tojWn gEhPRA callout--has-top-border\" data-testid=\"GenericCallout\">\n<figure class=\"AssetEmbedWrapper-eVDQiB byBkf asset-embed\">\n<div class=\"AssetEmbedAssetContainer-eJxoAx dBHGoQ asset-embed__asset-container\"><span class=\"SpanWrapper-umhxW lgCwTv responsive-asset AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset\"><picture class=\"ResponsiveImagePicture-cWuUZO dUOtEa AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset responsive-image\"><noscript><img decoding=\"async\" alt=\"Image may contain Fungus Plant Agaric and Mushroom\" class=\"ResponsiveImageContainer-eybHBd fptoWY responsive-image__image lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_1600%2Cc_limit\/521384007\" data-sizes=\"auto\" data-srcset=\"https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_120,c_limit\/521384007 120w, https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_240,c_limit\/521384007 240w, https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_320,c_limit\/521384007 320w, https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_640,c_limit\/521384007 640w, https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_960,c_limit\/521384007 960w, https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_1280,c_limit\/521384007 1280w, https:\/\/media.wired.com\/photos\/682b47fb41b24d55ad822bd6\/master\/w_1600,c_limit\/521384007 1600w\" data-sizes=\"100vw\"\/><\/noscript><\/picture><\/span><\/div>\n<p><span class=\"BaseWrap-sc-gjQpdd BaseText-ewhhUZ CaptionCredit-ejegDm iUEiRd isTgyB fNaHcW caption__credit\">Photograph: Getty Images<\/span><\/p>\n<\/figure>\n<\/div>\n<p class=\"paywall\">Marketed as brain food, lion\u2019s mane is rich in terpenes like hericenones and erinacines that boost the production of <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC4812798\/\" target=\"_blank\">the Nerve Growth Factor<\/a> (NGF), a protein vital for the maintenance and regeneration of neurons. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10675414\/\" target=\"_blank\">Preliminary research<\/a> also indicates it may aid in nerve regeneration, reduce the risk of cognitive decline, and alleviate symptoms of anxiety and depression. It\u2019s important to note, though, since it might contain phytoestrogens that could activate estrogen-sensitive cells, those with a history of breast cancer should consult a physician before using it.<\/p>\n<p class=\"paywall\">Maitake (also known as hen-of-the-wood) contains beta-glucans that have been shown to activate lymphocytes, natural killer (NK) cells, and T-helper cells. Researchers are investigating its potential to help regulate blood pressure and blood sugar, particularly in individuals with metabolic issues. Zeitlin recommends maitake\u2014and shiitake\u2014mushrooms for those who have a history of chronic illnesses.<\/p>\n<p class=\"paywall\">Reishi is studied for calming effects and possible support for blood sugar and lung function, thanks to its high polysaccharide content. &#8220;Reishi mushrooms are [for] a general wellness boost,&#8221; Zeitlin says. &#8220;If you&#8217;re feeling stressed out, you get colds frequently, or it&#8217;s spring season and your allergies are running amok, Reishi mushrooms are a supportive move.&#8221;<\/p>\n<p class=\"paywall\">Behind their umami-rich bite is a potent wellness profile: these mushrooms deliver lentinan, an immune-boosting polysaccharide, and eritadenine, known for supporting heart health by lowering cholesterol. Shiitake also reduces inflammation markers like CRP (C-reactive protein) and IgA (Immunoglobulin A). Plus, they\u2019re packed with B vitamins to support energy, metabolism, and cardiovascular health.<\/p>\n<p class=\"paywall\">This colorful mushroom gets its name from its resemblance to a turkey tail&#8217;s feather, and it&#8217;s one of the most researched macrofungus in oncology. Turkey tail is rich in protein-bound polysaccharides that stimulate immune responses, particularly in the function of T-cells and NK cells.<\/p>\n<p><h2 class=\"paywall\">When\u2019s the Best Time to Take Mushroom Supplements?<\/h2>\n<\/p>\n<figure class=\"AssetEmbedWrapper-eVDQiB byBkf asset-embed\">\n<div class=\"AssetEmbedAssetContainer-eJxoAx dBHGoQ asset-embed__asset-container\"><span class=\"SpanWrapper-umhxW lgCwTv responsive-asset AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset\"><picture class=\"ResponsiveImagePicture-cWuUZO dUOtEa AssetEmbedResponsiveAsset-cXBNxi lqMXz asset-embed__responsive-asset responsive-image\"><noscript><img decoding=\"async\" alt=\"A coffee bag\" class=\"ResponsiveImageContainer-eybHBd fptoWY responsive-image__image lazyload\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" data-src=\"https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_1600%2Cc_limit\/TopView_Think_GroundCoffee_072623.jpeg\" data-sizes=\"auto\" data-srcset=\"https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_120,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 120w, https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_240,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 240w, https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_320,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 320w, https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_640,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 640w, https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_960,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 960w, https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_1280,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 1280w, https:\/\/media.wired.com\/photos\/66ec5ea002e03ff8df7fb0e9\/master\/w_1600,c_limit\/TopView_Think_GroundCoffee_072623.jpeg 1600w\" data-sizes=\"100vw\"\/><\/noscript><\/picture><\/span><\/div>\n<p><span class=\"BaseWrap-sc-gjQpdd BaseText-ewhhUZ CaptionCredit-ejegDm iUEiRd isTgyB fNaHcW caption__credit\">Courtesy of Four Sigmatic<\/span><\/p>\n<\/figure>\n<p class=\"paywall\">Like most supplements, timing your mushroom intake depends on the specific variety and what you&#8217;re hoping to get out of it.<\/p>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"<p>From ancient remedies to your Amazon cart, mushroom supplements have traveled a circuitous road. They nourish the body, enhance the mind, and occasionally poison the unlucky. Their biochemical adaptability has intrigued Eastern cultures for centuries. The West has been slow to embrace mushrooms until the 21st century, propelled in part by endorsements from celebrities like [&hellip;]<\/p>\n","protected":false},"author":667,"featured_media":15311,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_uag_custom_page_level_css":"","_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[703],"tags":[899,181,770,1538,3787,744,3715],"class_list":["post-15310","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-technology","tag-food-and-drink","tag-health","tag-kitchen","tag-medicine","tag-nutrition","tag-shopping","tag-trends"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mushroom Supplements Are the Biohackers\u2019 Latest Fix (2025) | Unlock Informed Choices with Us<\/title>\n<meta name=\"description\" content=\"Curious about mushroom supplements? 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